Unique reversible thermo-sensitive characteristics
Synthetic origin and no batch-to-batch variation
Bio-degradable and non-toxic
Elastic behavior as collagen
Bio-functional applications through custom-made specific hydrogels
Our goal is to develop and to manufacture the best synthetic gels supporting and supplying our customers with a variety of applications to accelerate research and development in life science, healthcare and environment
Noviocell will build upon its expertise on synthetic hydrogel technologies. These hydrogels have a soft thermo-responsive helical poly-iso-cyano-peptides and are called PIC hydrogels.
The unique combination of a tunable bio-functionality and the bio-mechanics of the PIC-hydrogels make them excellent matrices.
Noviocell develops them into easy-to-use solutions for the biomedical research, the biotech, pharmaceutical industry, healthcare and food.
Noviocell BV is a highly innovative biotech company that was founded in 2015 as a spin-off from the Radboud University in Nijmegen. Noviocell BV has obtained the exclusive license in order to perform the research, development, the manufacturing and sales of the PIC-gels for a broad range of applications.
Noviocell is collaborating with a large number of universities located in The Netherlands and abroad, participating in various projects.
Noviocell’s main customers are cell biologists at academic institutions, government labs, hospitals, bio-tech- and pharmaceutical industries.
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This work illustrates for the first time the use of 111In-labelled PIC gels for diagnostic and monitoring purposes and describes the use of PIC in the (non-)splinted murine skin wound model. It was found that PIC gels remained in splinted and nonsplinted full-thickness skin wounds during wound repair.
Syntrix-BM kit can be used to prepare approximately 15 mL 3D cell culture matrix with embedded cells per kit.
Although common in biology, controlled stiffening of hydrogels in vitro is difficult to achieve; the required stimuli are commonly large and/or the stiffening amplitudes small. Here, we describe the hierarchical mechanics of ultra-responsive hybrid hydrogels composed of two synthetic networks, one semi-flexible and stress-responsive, the other flexible and thermoresponsive.
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