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Kouwer PHJ, Koepf M, Le Sage VAA, Jaspers M, van Buul AM, Eksteen-Akeroyd ZH, et al. Responsive biomimetic networks from polyisocyanopeptide hydrogels. Nature 2013.

Jaspers M, Dennison M, Mabesoone MFJ, MacKintosh FC, Rowan AE, Kouwer PHJ. Ultra-responsive soft matter from strain-stiffening hydrogels. Nat Commun. 2014.

Das RK, Gocheva V, Hammink R, Zouani OF, Rowan AE. Stress-stiffening-mediated stem-cell commitment switch in soft responsive hydrogels. Nat Mater 2015.

Bruekers, SMC, Jaspers M, Hendriks JMA, Kurniawan NA, Koenderink GH, Kouwer PHJ, Rowan AE, Huck WTS. Fibrin/fiber architecture influences cell spreading and differentiation. Cell Adhesion & Migration 2016.

Jaspers M, Pape ACH, Voets IK, Rowan AE, Portale G, Kouwer PHJ. Bundle formation in biomimectic hydrogels. Biomacromolecules 2016.

Zinkevich T, Venderbosch B, Jaspers M, Kouwer PHJ, Rowan AE, van Eck ERH, Kentgens APM. Solid state NMR characterization of tri-ethyleneglycol grafted polyisocynopeptides. Magn. Reson. Chem. 2016.

Mihaila S, Rowan AE, Feitz, WF, Oosterwijk E. Matrix-stiffness Driven Osteogenic Differentiation of Human Adipose Derived Stem Cells, TERMIS 2015.

Sun W, Eksteen-Akeroyd ZH, Nagelkerke A, Geutjes P, Zhou L, Wissing T, Wilson C, Feitz WF, Rowan AE, Oosterwijk E. Novel Polyisocyanopeptide Hydrogels for Rapid Vasculogenesis. TERMIS 2015.

L.M. Nibourg et al., Acta Ophthalmol.. 2016, 94, 721-729

L.M. Nibourg et al., Exp. Eye. Res. 2016, 143, 60-67

L. Ikonen et al., Biomed Research International. 2013, Article ID 285678

I. Kusters et al., PLoS ONE 2011, 6(5): e20435

A. Brizard et al., Angewandte Chemie, International Edition 2008, 47, 2063 – 20

F. Li et al. ChemPhysChem 2010, 11, 1956-196

M.R. de Jong et al., J. Control. Release, 132: e26-e27 (2008)

M. Montalti et al., Langmuir, 2006, 22, 2299 – 2303

K. J. C. van Bommel et al., Organic and Biomolecular Chemistry, 2005, 3, 2917 – 2920

M. De Loos et al., Org. Biomol. Chem. 2005, 3, 1631-1639

K.J.C. van Bommel et al. J. Control. Release 2005, 101, 287-290

A. Friggeri et al., Chemistry, a European Journal, 2005, 11, 5353 – 5361

A. Friggeri et al., Cosmetics & Toiletries 2005, 120: 67 – 76

K. J. C. van Bommel et al., Angewandte Chemie, International Edition 2004, 43, 1663 – 1667

A. Friggeri et al. J. Control. Release 2004, 97, 241-248

A. Heeres et al., Journal of the American Chemical Society, 2003, 125, 14252 – 14253

Jaspers M et al. Nonlinear mechanics of hybrid polymer networks that mimic the complex mechanical environment of cells. Nat Commun. 2017 May 25;8:15478.

Deshpande SR et al.Biomimetic Stress Sensitive Hydrogel Controlled by DNA Nanoswitches. Biomacromolecules. 2017 Oct 9;18(10):3310-3317.

Hammink R et al.Affinity-Based Purification of Polyisocyanopeptide Bioconjugates. Bioconjug Chem. 2017 Sep 15

Zimoch, J., Polyisocyanopeptide hydrogels: a novel thermo-responsive hydrogel re-vascularization and the development of organotypic structures, Acta Biomaterialia (2018)

Nehar Celikkin et al. 3D Printing of Thermoresponsive Polyisocyanide (PIC) Hydrogels as Bioink and Fugitive Material for Tissue Engineering Polymers 2018, 10, 555